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LuciErda 5mg (Erdafitinib)

LuciErda 5mg (Erdafitinib) is a targeted kinase inhibitor manufactured by Lucius Pharmaceuticals used to treat adults with locally advanced or metastatic urothelial carcinoma (bladder cancer). It requires confirmed FGFR3 or FGFR2 genetic alterations and prior platinum-based chemotherapy.

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Indications:
LuciErda is a precision oncology medicine that blocks fibroblast growth factor receptors (FGFR1–4), stopping tumor growth. It is prescribed for,
  • Patients with susceptible FGFR3 or FGFR2 genetic alterations.
  • Adults with locally advanced or metastatic urothelial carcinoma (bladder cancer).
  • Those whose cancer progressed during or following at least one line of platinum-containing chemotherapy.
Dosage:
  • Starting Dose: The standard starting dose is 8 mg taken orally once daily.
  • Adjustment: After 14 to 21 days, the dose may be increased to 9 mg once daily, based on serum phosphate levels and tolerability.
  • How to Take: Swallow whole with water, with or without food.
  • Interactions: Patients must avoid eating grapefruit or drinking grapefruit juice, as it can alter the metabolism of the drug.

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