{"id":181,"date":"2026-07-13T16:18:21","date_gmt":"2026-07-13T16:18:21","guid":{"rendered":"https:\/\/dcenbd.com\/?post_type=product&#038;p=181"},"modified":"2026-07-13T16:18:21","modified_gmt":"2026-07-13T16:18:21","slug":"luciafa-40mg-afatinib","status":"publish","type":"product","link":"https:\/\/dcenbd.com\/index.php\/product\/luciafa-40mg-afatinib\/","title":{"rendered":"LuciAfa 40mg (Afatinib)"},"content":{"rendered":"<h2>Description<\/h2>\n<p>LuciAfa 40mg is an oral tablet containing Afatinib 40 mg (as Afatinib dimaleate 59.12 mg), manufactured by Lucius Pharmaceuticals Ltd. It is a once-daily, second-generation tyrosine kinase inhibitor (TKI) used as a first-line treatment for metastatic non-small cell lung cancer (NSCLC) in patients whose tumors carry specific EGFR mutations.<br \/>\nLuciAfa contains the same active ingredient as\u00a0<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/201292s014lbl.pdf\" target=\"_blank\" rel=\"noopener\">Gilotrif\u00ae (Boehringer Ingelheim)<\/a>, first approved by the US FDA in July 2013.<\/p>\n<h2>How LuciAfa 40mg Works<\/h2>\n<p>Afatinib is an irreversible ErbB-family blocker. It permanently binds to and shuts down signaling from EGFR (ErbB1), HER2 (ErbB2), ErbB3, and ErbB4 receptors. By blocking these cancer-driving pathways, LuciAfa slows tumor growth and triggers cancer cell death \u2014 particularly in EGFR mutation-positive tumors.\u00a0<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fd638e5e-8032-e7ca-0179-95e96ab5d387&amp;audience=consumer\" target=\"_blank\" rel=\"noopener\">See the full afatinib drug profile on NIH DailyMed<\/a>.<\/p>\n<h2>Uses<\/h2>\n<p>LuciAfa 40mg is prescribed for:<\/p>\n<ul>\n<li>First-line treatment of metastatic NSCLC with non-resistant EGFR mutations (exon 19 deletions or exon 21 L858R substitutions, confirmed by an FDA-approved test)<\/li>\n<li>NSCLC with certain uncommon EGFR mutations (S768I, L861Q, G719X)<\/li>\n<li>Metastatic squamous NSCLC progressing after platinum-based chemotherapy<\/li>\n<\/ul>\n<p>A confirmed EGFR mutation diagnosis is required before starting treatment.<\/p>\n<h2>Dosage<\/h2>\n<table class=\"min-w-full border-collapse text-sm leading-[1.7] whitespace-normal\" width=\"1091\">\n<thead class=\"text-left\">\n<tr>\n<th class=\"text-text-100 border-b-0.5 border-border-300\/60 py-2 pr-4 align-top font-bold\" scope=\"col\">Detail<\/th>\n<th class=\"text-text-100 border-b-0.5 border-border-300\/60 py-2 pr-4 align-top font-bold\" scope=\"col\">Information<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"><strong>Standard dose<\/strong><\/td>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\">40 mg once daily<\/td>\n<\/tr>\n<tr>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"><strong>Administration<\/strong><\/td>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\">Take on an empty stomach \u2014 at least 1 hour before or 2 hours after food<\/td>\n<\/tr>\n<tr>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"><strong>Timing<\/strong><\/td>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\">Same time each day; do not double up on missed doses<\/td>\n<\/tr>\n<tr>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"><strong>Dose adjustment<\/strong><\/td>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\">May be reduced by 10 mg increments if side effects occur<\/td>\n<\/tr>\n<tr>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"><strong>Duration<\/strong><\/td>\n<td class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\">Continue until disease progression or intolerable side effects<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Always follow your oncologist\u2019s prescription. Full prescribing details are in the\u00a0<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/201292s014lbl.pdf\" target=\"_blank\" rel=\"noopener\">official FDA label for Gilotrif (afatinib)<\/a>. Storage: keep in a dry place at 20\u201325\u00b0C, away from light and out of reach of children.<\/p>\n<h2>Side Effects<\/h2>\n<p><strong>Common:<\/strong>\u00a0diarrhea, skin rash\/acne, mouth sores (stomatitis), nail infection (paronychia), dry skin, decreased appetite, nausea, vomiting.<\/p>\n<p><strong>Serious (seek medical help immediately):<\/strong>\u00a0severe or persistent diarrhea, severe skin blistering\/peeling, lung inflammation (breathlessness, cough, fever), liver problems, eye irritation or vision changes.<\/p>\n<p>Manage diarrhea by drinking plenty of fluids. Use gentle cleansers, moisturizers, and broad-spectrum sunscreen to reduce skin reactions. Avoid use during pregnancy and breastfeeding; use effective contraception during treatment and for at least 2 weeks after the last dose.<\/p>\n<h2>FAQ<\/h2>\n<p><strong>What is LuciAfa 40mg used for?<\/strong><br \/>\nLuciAfa 40mg is used as a first-line treatment for metastatic non-small cell lung cancer (NSCLC) in patients with specific EGFR gene mutations, and for squamous NSCLC that has progressed after chemotherapy.<\/p>\n<p><strong>Is LuciAfa the same as Gilotrif?<\/strong><br \/>\nYes. Both contain Afatinib as the active ingredient. LuciAfa is the Lucius Pharmaceuticals (Bangladesh) version of Gilotrif\u00ae\/Giotrif\u00ae.<\/p>\n<p><strong>How should I take LuciAfa 40mg?<\/strong><br \/>\nTake one 40 mg tablet once daily on an empty stomach \u2014 at least 1 hour before or 2 hours after eating, at the same time each day.<\/p>\n<p><strong>Do I need a test before starting?<\/strong><br \/>\nYes. A confirmed EGFR mutation-positive diagnosis via an FDA-approved test is required before treatment begins.<\/p>\n<p><strong>What is the most common side effect?<\/strong><br \/>\nDiarrhea and skin rash are the most common. Both are usually manageable with supportive care \u2014 drink fluids for diarrhea and use moisturizers and sunscreen for the skin.<\/p>\n<p><strong>Can the dose be lowered if side effects are severe?<\/strong><br \/>\nYes. Doctors may reduce the dose in 10 mg steps. Do not adjust the dose yourself \u2014 consult your oncologist.<\/p>\n<p><strong>Is it safe during pregnancy?<\/strong><br \/>\nNo. Afatinib can harm an unborn baby. Avoid during pregnancy and breastfeeding, and use effective contraception during and for 2 weeks after treatment.<\/p>\n<p><strong>How should it be stored?<\/strong><br \/>\nIn a dry place at 20\u201325\u00b0C, away from light, and out of reach of children.<\/p>\n","protected":false},"excerpt":{"rendered":"<h2>Specifications:<\/h2>\n<ul>\n<li>Active Ingredient: Afatinib 40 mg (as Afatinib dimaleate 59.12 mg)<\/li>\n<li>Drug Class: Second-generation Tyrosine Kinase Inhibitor (irreversible ErbB blocker)<\/li>\n<li>Manufacturer: Lucius Pharmaceuticals Ltd.<\/li>\n<li>Reference Brand: Gilotrif\u00ae \/ Giotrif\u00ae (Boehringer Ingelheim)<\/li>\n<li>Form: Film-coated oral tablet<\/li>\n<\/ul>\n<p class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\">Get\u00a0<strong>LuciAfa 40mg<\/strong> delivered directly to your doorstep \u2014 anywhere in the world. Dcenbd is a trusted source of certified cancer and specialty medicines, sourced directly from licensed manufacturers.<\/p>\n","protected":false},"featured_media":182,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[35],"product_cat":[19],"product_tag":[],"class_list":["post-181","product","type-product","status-publish","has-post-thumbnail","product_brand-dcenbd-export-all-kind-of-medicine-from-lucius-pharmaceuticals","product_cat-lung-cancer","desktop-align-left","tablet-align-left","mobile-align-left","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/product\/181","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/comments?post=181"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/media\/182"}],"wp:attachment":[{"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/media?parent=181"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=181"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=181"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/dcenbd.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}